Assoc Prof Peter Liu
(Sleep Cardiovascular, Metabolic and Endocrine Research Group)
Cardiovascular, Metabolic and Endocrine: Covers the cardiovascular, metabolic and endocrine consequences of obstructive sleep apnoea (OSA) and responses to treatment. Current cardiovascular research on understanding how arterial stiffness and central blood pressure is altered in OSA. Metabolic research is focussed on lipid metabolism and fat storage in relation to OSA and the Metabolic Syndrome and how testosterone and insulin affect body metabolism in men with OSA.
• One NHMRC fellowship to commence in 2009
• Newly awarded NHMRC Centre for Clinical Research Excellence
(CCRE) in Sleep to commence early 2009
With two major NHMRC project grants awarded in 2007 having commenced in 2008 and a further three being completed in 2009, the year ahead will hopefully clarify some of the cardiometabolic and endocrine consequences of CPAP therapy in men with obstructive sleep apnea. Two new NHMRC Project Grant applications were submitted.
A previous (2004-2006) NHMRC funded randomised controlled study to assess the effects of treatment of OSA with CPAP on lipid metabolism, lipid storage and markers of vascular oxidative stress is finishing in September. The results of this study will have important implications for clinical practice.
A study aimed at assessing cardiovascular responses to acute hypoxia exposure is completed and the results were published. MASPAP study – A NHMRC funded randomised controlled study to evaluate whether treatment of OSA with Mandibular Advancement Splints (MAS) results in an equivalent lowering of blood pressure compared with CPAP treatment is finishing in December.
The Group published thirteen manuscripts since 2008. These include five Original Research Papers and three Editorials
Assoc Prof Peter Liu MBBS (Hons) PhD FRACP
Assoc Prof Brendon Yee MBChB PhD FRACP FCCP
Staff Specialist, Respiratory and Sleep Physician
Dr Craig Phillips BSc GradDipCompSci PhD
Senior Researcher and NHMRC Fellow
Ms Camilla Hoyos BSc (Hons) MPH (Hons)
Dr Roo Killick MBBS MRCP FRACP
Respiratory & Sleep Physician
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